Throughout their senior year in high school, Zoe, Maddie, and Angela continue to share "instant messages" with one another about their day-to-day experiences as they consider college, sex, the importance of prom, and the inevitable end of their inseparable trio.

Haley continues her sophomore year at Hillsdale High, as she navigates a series of events that begin with a potentially disastrous New Year's Eve party and ends with what could be the spring break of her dreams.

Charlotte Usher has always struggled to fit in at her high school, and when Charlotte finds herself living in a parallel spiritual world after choking to death on a gummy bear, she tries to reconnect with the physical world while making new friends at her new school for the dead.

When sixteen-year-old Matt is falsely accused of threatening to blow up his high school and his friends turn against him, an unlikely classmate comes to his aid.

When aspiring actress Phoebe and her best friend, the brainy Harper, enter middle school, their friendship is briefly tested by Phoebe's admiration of some of the drama club students and the intensity of her first crush, but ultimately they find that their relationship can withstand the stresses of their expanding lives.

When chef and restaurateur Lillian starts hosting a monthly cooking class on Monday nights, her eight students begin to learn about food and each other while being personally transformed by new insights and friendships as rich as the dishes they create in the kitchen.

Serena van der Woodsen, Blair Waldorf, and Nate Archibald have been best friends for years, but their friendship is tested when both girls fall for Nate and he is forced to choose between, even if it means losing his best friends forever.

When first grader Lily gets into a fight with her two best friends, the experience teaches her a lot about friendship.

Two teenage loners become involved in the senior class play which helps them understand the meaning of friendship and betrayal.

Two unpopular girls try to break into the seventh grade clique system, even though they're not really sure they want to be popular at all.