Marnie and twelve of her closest friends gather together to share cookies, wine, and stories about their personal struggles and triumphs.

A group of friends rediscovers the power of friendship when they gather to mourn Tom's death in a terrorist attack, and to work out the mid-life crises that seem to be hitting them all at once.

Cousins Dahlia and Sunny Gordon were best friends growing up, but their lives were torn apart by Sunny's schizophrenia, until, after twenty-five years, Dahlia returns to seek her cousin's approval.

Clare Mann, the daughter of a middle-class Protestant family, and Sally Rose, a wealthy Jewish girl, become unlikely friends at Oberlin College in 1973, and form a bond that will sustain them through motherhood, marriage, divorce, and other challenges of life.

Two widows find themselves bonding over their joint knitting projects and help each other overcome their grief and move on with their lives.

Mary, trying to handle the suffocating grief she feels over the death of her young daughter, Stella, reluctantly joins a knitting circle and over the course of time learns about the problems others in the group have had to face, and comes to cherish them as friends.

Celia, Bree, Sally, and April, assigned to the same dorm their first year at Smith College, form a fast friendship, in spite of the differences between them, that carries them into an uncertain future.

Laurel McBane, who works with her best friends Emma, Mac, and Parker at a wedding planning company, harbors a crush on Parker's older brother Delaney, a successful lawyer who she is convinced is out of her league, but when the two share a passionate kiss, she wonders if it could lead to something more.

After the death of her wealthy husband, Tracey decides to invite her daughter and two friends she has had since high school on a sailing trip in the Caribbean, but after a storm hits, their relaxing vacation quickly turns into a fight for survival as they brave the elements and defend themselves against pirate attacks.

Eight women from a small town in Wisconsin decide to leave their lives behind and take a pilgrimage across the United States, inspiring women from all walks of life and teaching them about life, love, and friendship.